Time to Market New product

New product development Time to market

New Product Development

New Product Development

Tracing Pharmaeutical from History

• The History of Pharmaceutical Indus can be traced to 1600 BC In around 1640 BC Dhanvantari wrote a treatise on Medicine, Pharmaceutics, & surgery. AYURVEDA SUSHRUTHA CHARAKA During around 500 BC Buddhist Monks spread to the rest of the world
• Pharmaceutical Industry an overview Modern day Allopathic Medication More than 350 years old Research & Development in later part of 19 th Century and 20 th Century In 1930 Penicillin & Insulin were discovered. Modern day Allopathic Medication
•   Pharmaceutical Industry an overview In 1901 Acharya P.C. Ray started first Indian Pharmaceutical company Till Independence Multinational were directly operating In 1970s Product patent was replaced by process patent Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview !970s saw the emergence of Indian Pharmaceutical Industry This led to the expansion of Bulk Drug Industry Various subsidies and infrastructural facilities enabled the expansion & spread of the Industry in various states. Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview 70s and 80 also saw the launch of new products in the Cardio Vascular, Neuro, Psycho-somatic, Gastro Renal, Anti Fungal and Anti Imflammatory segments. New products like Co-Trimoxazole, Diltiazem, Diclofenac Sodium were some of the products launched. Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview 70s and 80 also saw the, the beginning of exports to Asia, Africa,Europe,and Latin America of Bulk Drugs. More and more organization were able to get USFDA & WHO GMP certification. Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview WTO & GATT Resulting in more application for patent 35,218 Applications for patent were filed in the year 2008-09. 6040 from domestic, & 29,178 from foreign applicant R&D being out sourced to India by MNCs Indian Pharmaceutical Scenario
• Pharmaceutical Industry an overview Present Indian Market Size $ 8 Billion Rs. 400 Billion Indian Pharmaceutical Scenario
• Pharmaceutical Industry an overview Pharmaceutical Industry largest contributor after the Agriculture sector. To the Indian economy. Still growing @ 10 to 11% Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview Present global market size $ 825 Billion growing @ 4 to 6 % India 3 rd largest producer of Pharmaceuticals having 10% of the global share. Indian Pharmaceutical Scenario
•   Pharmaceutical Industry an overview Cardiovascular segment dominates the sales with 50% Share Anti Diabetic segment has a share of 22 % Indian Pharmaceutical Scenario

API A glance

This [post  can help to choose products for development and setting up marketing strategies for APIs in domestic and overseas market.

• Globally there are over 7000 APIs are active in 2013 • Altogether APIs creates USD 120 billion world market • Which is 12% of world pharmaceuticals market • That is around USD 1000 billion • World market of APIs is growing at the rate of 8% • US is biggest market with around 45% share of the world market .

• INDIAN APIs INDUSTRY • India has around 2300 APIs manufacturing units •Which produces around 1500 APIs •For domestic and International market •Indian APIs Industry is worth USD 9 billion in 2013 •Out of which USD 5 billion exported across the world •Rest USD 4 billion goes for formulation •Out of which USD 2 billion goes for the formulation for export •Rest USD 2 billion goes for domestic formulation manufacturing .

• INDIAN APIs INDUSTRY: ASSUMPTIONS • The basis of the study is export data of APIs and formulations and articles published in different journals for the year 2012-13 • The export data suggest USD 5 billion worth APIs goes for export we assume the domestic consumption (for domestic and export formulation) is USD 4 billion or 80% of the export business • It must be noted that while USD 2 billion APIs results in USD 10 billion export of formulation while the same value of APIs creates USD 18-20 billion Indian domestic formulation markets .

• INDIAN APIs INDUSTRY • Out of 1500 APIs produced in India around 1000 goes for export • Top 50 APIs contributes 50% of the industry • Top 100 APIs accounts for 70% of the industry • Top 200 APIs constitutes 85 % of the industry • Top 500 APIs represents 95% of the industry .

• The TOP 500 APIs • Top 500 APIs accounts for 95% of business • But the study leaves some APIs which does more than USD 5 million in export of formulation like — DIDANOSINE, MUPIROCIN, CYCLOSERINE, IPRATROPIUM, ZIPRASIDOE, WARFARINSODIUM, GENTAMICIN,BECLOMETHASONE, IRINOTECAN, ZONISAMIDE, MISOPROSTOL, INDAPAMIDE, AMYLMETACRESOL, LEVODOPA, ATRACURIUM, RILUZOLE, PROPOFOL, ISOTRETINOIN, OXALIPLATIN, LEVONORGESTREL, ZAFIRLUKAST, ALPRAZOLAM, TROSPIUMCHLORIDE, AZELASTINE, DOXORUBICIN, VECURONIUM, ESTRADIOL, NORETHINDRONE, FONDAPARINUX, ETOMIDATE, CEVIMELINE, OCTREOTIDE, ETHINYLESTRADIOL, RITUXIMAB, TIAGABINE, and NORGESTIMATE and CISPLATIN.

• THE MILLION DOLLAR CLUB • There are 430 APIs whose export is above USD 1 Million • The club represents 93% of the Industry • We further filter the list and leave APIs whose average price is below USD 25/kg and that leaves few major products whose export is considerable like—- NAPROXEN, SALICYLIC ACID, TRICLOSAN, ERYTHROMYCIN, RANITIDINE, POVIDONE IODINE, COTRIMOXAZOLE, CAFFEINE, DICLOFENAC, METRONIDAZOLE, PERMETHRIN, GUAIFENESIN, SULFAMETHOXAZOLE, NICOTINAMIDE, CHLORHEXIDINE, ACETAMINOPHEN, METFORMIN, NIACIN, GLYCINE, BENZYL CHLORIDE, CLOXACILLIN, ZINCOXIDE, AMPICILLIN, CALCIUM CARBONATE and ALUMINIUM HYDROXIDE

· THE MILLION DOLLAR CLUB… • Now we are left with 355 APIs for our analysis • Which represents around 75% of the industry • Further we eliminate the APIs whose export is less than 500 Kg •

• The club represents 93% of the Industry • We further filter the list and leave APIs whose average price is below USD 25/kg and that leaves few major products whose export is considerable like—- NAPROXEN, SALICYLIC ACID, TRICLOSAN, ERYTHROMYCIN, RANITIDINE, POVIDONE IODINE, COTRIMOXAZOLE, CAFFEINE, DICLOFENAC, METRONIDAZOLE, PERMETHRIN, GUAIFENESIN, SULFAMETHOXAZOLE, NICOTINAMIDE, CHLORHEXIDINE, ACETAMINOPHEN, METFORMIN, NIACIN, GLYCINE, BENZYL CHLORIDE, CLOXACILLIN, ZINCOXIDE, AMPICILLIN, CALCIUM CARBONATE and ALUMINIUM HYDROXIDE

•   THE MILLION DOLLAR CLUB… • Now we are left with 355 APIs for our analysis • Which represents around 75% of the industry • Further we eliminate the APIs whose export is less than 500 Kg • And that leaves some valued products like ROCURONIUM, TACROLIMUS, FIDAXOMICIN, ADAPALENE and SIROLIMUS • Now we are have left with 320 APIs which represents 70% of the industry •

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